Tuberculosis (TB) is one of the oldest infectious diseases in human history and remains a major global health threat. According to the World Health Organization (WHO), an estimated 10.7 million people developed TB in 2024, and approximately 1.23 million died from the disease. Despite advances in medicine that have made TB both preventable and treatable, it remains the world’s leading infectious killer.
The burden of TB is concentrated in low- and middle-income countries (LMICs) with fragile health systems. More than 80% of all TB cases occur in settings where access to diagnostic tools and treatment remains limited, making timely diagnosis and successful treatment difficult. When the critical window for treatment is missed, transmission can accelerate rapidly, leading to wider outbreaks and increased mortality.
TB is also a global concern because it is no longer confined to a small number of countries. OECD countries continue to report approximately 100,000 to 150,000 TB cases each year, and due to airborne nature, the disease has the potential to spread globally.
In addition, multidrug-resistant tuberculosis (MDR-TB), which does not respond to standard treatment, has become increasingly widespread. According to the WHO, 390,000 people developed MDR-TB in 2024. However access to care remains even more limited, with only 42% of those affected receiving treatment. This is highlight the need to recognized TB not merely as a public health issue affecting certain regions or countries, but as a global health security challenge that requiring coordinated international action.
In response to these challenges, the RIGHT Foundation has developed a comprehensive support portfolio spanning the full continuum of TB response—from prevention and diagnosis to treatment—and continues its efforts to end TB. RIGHT has consistently supported projects that address urgent unmet needs in global health, including R&D for digital systems designed for use in low-resource settings, as well as initiatives focused on MDR-TB.
Outlined below are the TB projects supported by RIGHT.
Vaccine
Therapeutics
– Safety Assessment of TTCA Antitubercular Agents
Diagnostics
– POCT for Multidrug-Resistant TB
– POCT for Pyrazinamide (PZA) Susceptibility Testing
Digital Health
– Quantifying the Added Value of Lunit Software in Advancing TB Elimination Efforts
In addition, many other organizations are working toward ending TB. To hightlight global efforts, two leading institutions are introduced below.
First, the International Tuberculosis Research Center (ITRC), which participated as a collaborating research institution in one of RIGHT’s supported projects, conduct a wide range of studies aimed at eliminating TB. Through its website, ITRC provides access to the latest domestic and international research, including clinical studies, pathology, and vaccine development.
The Stop TB Partnership is one of the most influential global platforms in the fight against TB, bringing together the WHO, national governments, and private-sector partners to advance collective action toward ending TB. In 2026, it is leading a global campaign for World TB Day under the theme,: “Yes! We can End TB! Led by countries. Powered by people.”
※Sources
<Global tuberculosis report 2025 – WHO>
<RIGHT Foundation and Bioneer: WHO Prequalification for Drug-Resistant TB Diagnostic Kit for LMIC Supply Expected Next Year>
https://www.sedaily.com/article/13862683
<Bioneer’s TB Diagnostic Solution Draws Attention at the 2024 Union World Conference on Lung Health>
https://www.hankyung.com/article/202411190050P
<Leading Development of a Patch-Type TB Vaccine Designed for Efficacy, Safety, and Affordability>
https://www.yakup.com/news/index.html?mode=view&pmode=&cat=&cat2=&nid=250657
<STOP TB Partnership -WORLD TB DAY 2026>
https://www.stoptb.org/what-we-do/advocate-endtb/world-tb-day/world-tb-day-2026