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AI-driven Platform for Anti-Tubercular Drug Discovery

Award type :
Product Development Award
Product type :
Digital Health
Award year :
2021
Project start date :
09 / 16 / 2021
Project end date :
09 / 30 / 2022
Project duration (months) :
12
Development stage :
Early Validation
Target disease :
Tuberculosis
Region served :
World
Recipient organization / Country of funding recipient organization :
Standigm / Republic of Korea
Collaborator(s) / Country :
Institut Pasteur Korea (IPK) / Republic of Korea
Funding amount(KRW) :
300,000,000

In collaboration with Institut Pasteur Korea, Standigm aims to assess the implementation and validation of an AI-based drug discovery platform for discovering new tuberculosis treatment drug leads with automated early discovery. With the aid of hit clustering, compound selection, in vitro assay testing, and prioritization of the final candidates, Standigm aims to validate the automated approach and refine the algorithm. In response to the urgent need for new anti-tubercular drugs, particularly in face of multidrug-resistant tuberculosis, the assessment of such AI-driven drug discovery platforms has the potential to accelerate the overall drug discovery process and to be applied widely to drug discovery in various disease areas.