{"id":7668,"date":"2025-01-14T14:56:22","date_gmt":"2025-01-14T05:56:22","guid":{"rendered":"https:\/\/rightfoundation.kr\/en\/?p=7668"},"modified":"2026-01-16T14:22:42","modified_gmt":"2026-01-16T05:22:42","slug":"development-of-a-therapeutic-anti-dengue-polymeric-igg-antibody","status":"publish","type":"post","link":"https:\/\/rightfoundation.kr\/en\/development-of-a-therapeutic-anti-dengue-polymeric-igg-antibody\/","title":{"rendered":"Development of a Therapeutic Anti-Dengue Polymeric IgG Antibody"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"7668\" class=\"elementor elementor-7668\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-749eb4c5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"749eb4c5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-572e761a\" data-id=\"572e761a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e58c318 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"7e58c318\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Award type :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Product Development Award<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-64ca934 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"64ca934\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Product type :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Therapeutics<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-72f9944e elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"72f9944e\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Award year :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">2021<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1115bc04 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"1115bc04\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project start date :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">10 \/ 27\/ 2021<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-234253f6 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"234253f6\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project end date :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">10 \/ 27\/ 2023<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76eeb0c5 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"76eeb0c5\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project duration (months) :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">24<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7908025f elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"7908025f\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Development stage :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Preclinical<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-542a43f3\" data-id=\"542a43f3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2bca3fef elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"2bca3fef\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Target disease :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Dengue<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a74ba23 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"6a74ba23\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Region served :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">World<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-28a6b066 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"28a6b066\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Recipient organization \/ Country of funding recipient organization :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">St George's University of London (SGUL) \/ UK<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3dec1239 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"3dec1239\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Collaborator(s) \/ Country :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Jeonbuk National University \/ Republic of Korea, Genecell Biotech \/ Republic of Korea<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2cd5792e elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"2cd5792e\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Funding amount(KRW) :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">223,738,000<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-62c7595e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"62c7595e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-17af1f17\" data-id=\"17af1f17\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1365459e elementor-widget elementor-widget-text-editor\" data-id=\"1365459e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>In order to eliminate the risk of antibody dependent enhancement (ADE), St. George\u2019s University of London is developing a polymeric anti-dengue IgG construct with LALA mutation, in collaboration with Jeonbuk National University and Genecell Biotech. The project aims to develop an innovative polymeric antibody construct that is superior to conventional neutralizing monoclonal IgG antibodies. The new plant-based protein expression system promises broader applications for reducing manufacturing price, thereby making antibody therapies accessible to patients in LMICs.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Award type : Product Development Award Product type : Therapeutics Award year : 2021 Project start date : 10 \/ 27\/ 2021 Project end date : 10 \/ 27\/ 2023 Project duration (months) : 24 Development stage : Preclinical Target disease : Dengue Region served : World Recipient organization \/ Country of funding recipient organization&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[8],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/7668"}],"collection":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/comments?post=7668"}],"version-history":[{"count":40,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/7668\/revisions"}],"predecessor-version":[{"id":11166,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/7668\/revisions\/11166"}],"wp:attachment":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/media?parent=7668"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/categories?post=7668"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/tags?post=7668"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}