{"id":11349,"date":"2026-01-27T11:41:00","date_gmt":"2026-01-27T02:41:00","guid":{"rendered":"https:\/\/rightfoundation.kr\/en\/?p=11349"},"modified":"2026-01-27T11:53:02","modified_gmt":"2026-01-27T02:53:02","slug":"development-of-telacebec-for-buruli-ulcer","status":"publish","type":"post","link":"https:\/\/rightfoundation.kr\/en\/development-of-telacebec-for-buruli-ulcer\/","title":{"rendered":"Development of Telacebec for Buruli Ulcer"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"11349\" class=\"elementor elementor-11349\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-749eb4c5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"749eb4c5\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-572e761a\" data-id=\"572e761a\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7e58c318 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"7e58c318\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Award type :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Product Development Award<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-64ca934 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"64ca934\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Product type :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Therapeutics<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-72f9944e elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"72f9944e\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Award year :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">2025<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1115bc04 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"1115bc04\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project start date :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">08 \/ 13 \/ 2025<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-234253f6 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"234253f6\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project end date :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">-<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-76eeb0c5 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"76eeb0c5\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Project duration (months) :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">-<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7908025f elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"7908025f\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Development stage :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Phase 2<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-top-column elementor-element elementor-element-542a43f3\" data-id=\"542a43f3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2bca3fef elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"2bca3fef\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Target disease :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Buruli Ulcer<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6a74ba23 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"6a74ba23\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Region served :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">West Africa, Central and East Asia, the Pacific (excluding high-income countries), Australia<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-28a6b066 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"28a6b066\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Recipient organization \/ Country of funding recipient organization :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Global Alliance for TB Drug Development (TB Alliance) \/ USA<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3dec1239 elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"3dec1239\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Collaborator(s) \/ Country :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">Qurient \/ Republic of Korea,\nBarwon Health \/ Australia<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2cd5792e elementor-widget elementor-widget-stad_for_elementor_heading\" data-id=\"2cd5792e\" data-element_type=\"widget\" data-widget_type=\"stad_for_elementor_heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\r\n\t<div class=\"stad-heading stad-heading-dual-content stad-padding-0 stad-margin-0\">\t\t\t\t\t<span class=\"stad-heading-dual-before-content-text stad-heading-content-text stad-inline-block\">Funding amount(KRW) :<\/span>\r\n\t\t\t\t\t\t\t<br class=\"stad-heading-dual-after-content-text-br\">\r\n\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text stad-heading-content-text stad-inline-block\">\r\n\t\t\t\t\t\t\t\t\t<span class=\"stad-heading-dual-content-after-text-content\">2,885,030,618<\/span>\r\n\t\t\t\t\t\t\t<\/span>\r\n\t\t\t<\/div>\t\t\r\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-62c7595e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"62c7595e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-17af1f17\" data-id=\"17af1f17\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1365459e elementor-widget elementor-widget-text-editor\" data-id=\"1365459e\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.12.1 - 02-04-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>TB Alliance, in collaboration with Korean innovator Qurient and Barwon Health, is developing telacebec for Buruli ulcer, a neglected tropical disease caused by Mycobacterium ulcerans that primarily affects children under 15 in sub-Saharan Africa. Current standard treatment requires once-daily rifampicin and twice-daily clarithromycin for eight weeks, creating burdens due to lengthy duration, complex administration, and poor adherence. Telacebec, originally discovered by Qurient for tuberculosis and with demonstrated Phase I and II safety, shows exceptional potency against M. ulcerans in preclinical studies, suggesting potential for simplified four-week monotherapy. This Phase II trial in Australia will enroll approximately 80 adults with broader inclusion criteria than previous studies to demonstrate safety and efficacy, including pharmacokinetic analysis to support future pediatric dosing. The streamlined treatment could improve adherence, reduce healthcare burden, and accelerate healing while supporting antibiotic stewardship through targeted mycobacterial activity.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Award type : Product Development Award Product type : Therapeutics Award year : 2025 Project start date : 08 \/ 13 \/ 2025 Project end date : &#8211; Project duration (months) : &#8211; Development stage : Phase 2 Target disease : Buruli Ulcer Region served : West Africa, Central and East Asia, the Pacific (excluding&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[8],"tags":[],"jetpack_featured_media_url":"","_links":{"self":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/11349"}],"collection":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/comments?post=11349"}],"version-history":[{"count":4,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/11349\/revisions"}],"predecessor-version":[{"id":11353,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/posts\/11349\/revisions\/11353"}],"wp:attachment":[{"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/media?parent=11349"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/categories?post=11349"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/rightfoundation.kr\/en\/wp-json\/wp\/v2\/tags?post=11349"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}